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Article

A master regulator sigmaB governs osmotic and oxidative response as well as differentiation via a network of sigma factors in Streptomyces coelicolor.

Molecular microbiology - 1 Sept 2005

Lee Eun-Jin, Karoonuthaisiri Nitsara, Kim Hyo-Sub, Park Joo-Hong, Cha Chang-Jun, Kao Camilla M, Roe Jung-Hye

Abstract excerpt

The differentiating bacterium Streptomyces coelicolor harbours some 66 sigma factors, which support its complex life cycle. sigma(B), a functional homologue of sigma(S) from Escherichia coli, controls both osmoprotection and differentiation in S. coelicolor A3(2). Microarray analysis revealed sigma(B)-dependent induction of more than 280 genes by 0.2 M KCl. These genes encode several sigma factors, oxidative...

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Identifiers

PMID: 16101999
DOI: 10.1111/j.1365-2958.2005.04761.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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A master regulator sigmaB governs osmotic and oxidative response as well as differentiation via a network of sigma factors in Streptomyces coelicolor.PMID 16101999Read ↗

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