Article
HaploChIP: an in vivo assay.
Methods in molecular biology (Clifton, N.J.) - 1 Jan 2005
Charles Knight Julian
Abstract excerpt
The characterization of protein-deoxyribonucleic acid (DNA) interactions occurring at an allele-specific level is important to resolving the functional consequences of genetic variation in non-coding DNA for gene expression and regulation. The approach of haplotype-specific chromatin immunoprecipitation (i.e., haploChIP) resolves in living cells relative protein-DNA binding to a particular allele through...
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