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Article

At least two regions of the oncoprotein Tre2 are involved in its lack of GAP activity.

Biochemical and biophysical research communications - 30 Sept 2005

Bizimungu Christelle, Vandenbol Micheline

Abstract excerpt

The product of the human Tre2 oncogene is structurally related to the Ypt/Rab GTPase-activating proteins (Ypt/Rab GAPs). Particularly, the oncoprotein shares with the yeast proteins Msb3p and Msb4p, and with the human protein RN-tre the highly conserved TBC domain, forming the catalytically active domain of Ypt/Rab GAPs. Yet, the Tre2 oncogene seems to encode a nonfunctional Rab GAP. As regions flanking the TBC...

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Identifiers

PMID: 16099424
DOI: 10.1016/j.bbrc.2005.07.159

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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