Article
[HBs antigen mutants: prevalence, clinical and diagnostic implications].
Pathologie-biologie - 1 Jan 2000
Roque-Afonso A-M, Ferey M-P, Belkhiri D, Dussaix E
Abstract excerpt
The serological diagnosis hepatitis B (HBV) infections relies mainly on the detection of the small surface antigen (HBsAg). Immuno-enzymatic assays use antibodies directed against epitopes of the major hydrophilic region, in particular against a determinant. Genetic variants have been detected in vaccinated children, liver transplanted patients receiving anti-HBs immunoprophylaxis and chronic carriers with an...
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