A method for assessing patterns of familial resemblance in complex human pedigrees, with an application to the nevus-count data in Utah kindreds.

Article

A method for assessing patterns of familial resemblance in complex human pedigrees, with an application to the nevus-count data in Utah kindreds.

American journal of human genetics - 1 Jul 1992

Zhao L P, Grove J, Quiaoit F

Abstract excerpt

An analytic method is described for estimating phenotypic correlations between pairs of members of specific relationships in pedigrees. In estimating correlations, this new method allows simultaneous adjustment for available covariates such as age, gender, environmental factors, and variables reflecting ascertainment mode, through mean- and variance-regression models. The estimated correlations and regression...

Topics

Dysplastic Nevus Syndrome
Female
Humans
Male
Melanoma
Multivariate Analysis
Nevus
Pedigree
Phenotype
Regression Analysis
Skin Neoplasms
Utah

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