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Article

The shared epitope is a marker of severity associated with selection for, but not with response to, infliximab in a large rheumatoid arthritis population.

Annals of the rheumatic diseases - 1 Mar 2006

Marotte H, Pallot-Prades B, Grange L, Tebib J, Gaudin P, Alexandre C, Blond J L, Cazalis M A, Mougin B, Miossec P

Abstract excerpt

OBJECTIVE: To determine whether joint destruction, indication for, and response to infliximab in rheumatoid arthritis are associated with the shared epitope (SE) or selected cytokine gene polymorphisms (interleukin (IL) 1B, IL1-RN, and tumour necrosis alpha). METHODS: In a large rheumatoid arthritis population of 930 patients from the same area (Rhône-Alpes, France), patients with (n = 198) or without infliximab...

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Share to Antibodies, Monoclonal
Share to Antirheumatic Agents

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Arthritis, Rheumatoid

Share to Cytokines

Share to Epitopes

Share to Infliximab

Share to Patient Selection

Share to Severity of Illness Index

Source

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Identifiers

PMID: 16096333
DOI: 10.1136/ard.2005.037150
PMCID: PMC1798045

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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