Article
Inherited disorders of the IL-12-IFN-gamma axis in patients with disseminated BCG infection.
European journal of pediatrics - 1 Dec 2005
Mansouri Davood, Adimi Parisa, Mirsaeidi Mehdi, Mansouri Nahal, Khalilzadeh Soheila, Masjedi Mohammad R, Adimi Parvaneh, Tabarsi Payam, Naderi Mohammad, Filipe-Santos Orchidée, Vogt Guillaume, de Beaucoudrey Ludovic, Bustamante Jacinta, Chapgier Ariane, Feinberg Jacqueline, Velayati Ali A, Casanova Jean-Laurent
Abstract excerpt
Disseminated BCG infection is a rare complication of vaccination that occurs in patients with impaired immunity. In recent years, a series of inherited disorders of the IL-12-IFN-gamma axis have been described that predispose affected individuals to disseminated disease caused by BCG, environmental Mycobacteria, and non-typhoidal Salmonella. The routine immunological work-up of these patients is normal and the...
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