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Mycosubtilin Overproduction by <i>Bacillus subtilis</i> BBG100 Enhances the Organism's Antagonistic and Biocontrol Activities

1 Aug 2005

Abstract excerpt

A Bacillus subtilis derivative was obtained from strain ATCC 6633 by replacement of the native promoter of the mycosubtilin operon by a constitutive promoter originating from the replication gene repU of the Staphylococcus aureus plasmid pUB110. The recombinant strain, designated BBG100, produced up to 15-fold more mycosubtilin than the wild type produced. The overproducing phenotype was related to enhancement of...

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PMID: 16085851
DOI: 10.1128/aem.71.8.4577-4584.2005

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