Effect of<i>pps</i>disruption and constitutive expression of<i>srfA</i>on surfactin productivity, spreading and antagonistic properties of<i>Bacillus subtilis</i>168 derivatives

Abstract excerpt

AIMS: To analyse the effects of plipastatin operon disruption and constitutive expression of surfactin operon in Bacillus subtilis 168 on surfactin productivity, in vitro invasive growth and antagonism against fungi. METHODS AND RESULTS: The srfA native promoter was replaced by the constitutive promoter P(repU) in B. subtilis 168 after integration of a functional sfp gene. Moreover, the plipastatin synthesis was...

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