Article
Comparison between sequence analysis and a line probe assay for testing genotypic resistance of human immunodeficiency virus type 1 to antiretroviral drugs.
Journal of clinical microbiology - 1 Aug 2005
García-Bujalance S, de Guevara C Ladrón, González-García J, Arribas J R, Gutiérrez A
Abstract excerpt
The purpose of this study was to compare a line probe assay (LiPA) with sequence analysis for the detection of mutations conferring resistance to nucleoside and non-nucleoside inhibitors in human immunodeficiency reverse transcriptase and protease inhibitors. The limitations for interpreting LiPA make it unacceptable for routine clinical practice.
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