Article
The effects of dexamethasone on fibronectin expression in cultured human trabecular meshwork cells.
Investigative ophthalmology & visual science - 1 Jun 1992
Steely H T, Browder S L, Julian M B, Miggans S T, Wilson K L, Clark A F
Abstract excerpt
Topical administration of glucocorticoids to the eye can lead to the development of ocular hypertension. This increase in intraocular pressure is caused by the heightened resistance to flow of aqueous humor from the eye, presumably at the trabecular meshwork (TM). This study reports the effects of dexamethasone (DEX) on the expression of the extracellular matrix protein fibronectin (FN) in cultured human TM cells...
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