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Article

Glucocorticoid-Induced Changes in the Global Gene Expression of Lens Epithelial Cells

1 Feb 2005

Abstract excerpt

AIMS: Clinically, steroid use is accompanied by a risk for posterior subcapsular cataracts (PSCs). PSC possibly involves perturbation of lens epithelial cell proliferation and differentiation; however, the underlying mechanism is unknown. In this study, we aimed to characterize changes in gene expression in human lens epithelial cells exposed to glucocorticoid using DNA microarray hybridization. METHODS: Human...

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PMID: 15718824
DOI: 10.1089/jop.2005.21.11

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