Article
Comparative evaluation of the immune status of congenitally athymic and euthymic rat strains bred and maintained at different institutes: 2. Athymic rats.
Journal of experimental animal science - 1 Mar 1992
Schuurman H J, Bell E B, Gärtner K, Hedrich H J, Hansen A K, Kruijt B C, de Vrey P, Leyten R, Maeder S J, Moutier R
Abstract excerpt
We performed a comparative evaluation of the immune status, focused on the T-cell system, in congenitally athymic rat strains. From 11 institutes around the world, we sampled 15 groups of animals at ages of 1 1/2-2 months and 1/2 year. The analysis included weight of body and spleen; antibody response and delayed-type hypersensitivity response after immunization with ovalbumin; and (immuno)histology of spleen,...
Topics
- Animals
- Cluster Analysis
- Female
- Lymphoid Tissue
- Male
- Mice, Nude
- Mutation
- Rats
