Article
Both alleles of the M235T polymorphism of the angiotensinogen gene can be a risk factor for myocardial infarction.
Clinical genetics - 1 Jul 2001
Fernández-Arcás N, Dieguez-Lucena J L, Muñoz-Morán E, Ruiz-Galdón M, Espinosa-Caliani S, Aranda-Lara P, Rius-Diaz F, Gaitán-Arroyo M J, De Teresa-Galván E, Reyes-Engel A
Abstract excerpt
We have studied the role of three polymorphic genes of the renin-angiotensin system (RAS) as independent risk factors for myocardial infarction (MI) and their correlation with three of the major coronary risk factors: serum cholesterol (CH), hypertension (HT) and smoking (SM). A population of 392 men was genotyped for the M235T polymorphism of the angiotensinogen (AGT) gene, the insertion/deletion of the...
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