Article
Transferrin receptor-1 and 2 expression in chronic lymphocytic leukemia.
Leukemia research - 1 Feb 2006
Smilevska Tatjana, Stamatopoulos Kostas, Samara Maria, Belessi Chrysoula, Tsompanakou Aliki, Paterakis George, Stavroyianni Niki, Athanasiadou Ioanna, Chiotoglou Ioanna, Hadzidimitriou Anastasia, Athanasiadou Anastasia, Douka Vassiliki, Saloum Riad, Laoutaris Nikolaos, Anagnostopoulos Achilles, Fassas Athanasios, Stathakis Nikolaos, Kollia Panagoula
Abstract excerpt
Transferrin receptor (TfR)-1 and 2 mRNA and CD71 (TfR1) expression was analyzed in 118 CLL patients. Ninety-five out of 109 analyzed cases expressed CD71, mostly at a high level; 60% of CD71 (+) cases were IGH-mutated. All samples were TfR1 mRNA (+); TfR2-alpha/beta mRNA was detected in, respectively, 52/102 and 100/109 cases. Competitive RT-PCR showed widely divergent levels of TfR1 mRNA in cases with high CD71...
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