Article
A Nucleic Acid Biosensor for Detection of Hepatitis C Virus Genotype 1a Using Poly(L-Glutamic Acid)-Modified Electrode.
Applied biochemistry and biotechnology - 1 Jul 2015
Donmez Soner, Arslan Fatma, Arslan Halit
Abstract excerpt
An electrochemical nucleic acid biosensor based on label-free DNA detection method was prepared for the first time by using electropolymerized poly(L-glutamic acid)-modified pencil graphite electrode (PGA/PGE) for detection of hepatitis C virus genotype 1a (HCV1a). Inosine-substituted 20-mer probes related to the HCV1a were immobilized onto PGA/PGE surface by covalent linking with the formation of amide bonds....
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