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Article

Real-time PCR screening for 16S rRNA mutations associated with resistance to tetracycline in Helicobacter pylori.

Antimicrobial agents and chemotherapy - 1 Aug 2005

Glocker Erik, Berning Marco, Gerrits Monique M, Kusters Johannes G, Kist Manfred

Abstract excerpt

The effectiveness of recommended first-line therapies for Helicobacter pylori infections is decreasing due to the occurrence of resistance to metronidazole and/or clarithromycin. Quadruple therapies, which include tetracycline and a bismuth salt, are useful alternative regimens. However, resistance to tetracycline, mainly caused by mutations in the 16S rRNA genes (rrnA and rrnB) affecting nucleotides 926 to 928,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 16048919
DOI: 10.1128/AAC.49.8.3166-3170.2005
PMCID: PMC1196286

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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