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Article

Approximating the coalescent with recombination.

Philosophical transactions of the Royal Society of London. Series B, Biological sciences - 29 Jul 2005

McVean Gilean A T, Cardin Niall J

Abstract excerpt

The coalescent with recombination describes the distribution of genealogical histories and resulting patterns of genetic variation in samples of DNA sequences from natural populations. However, using the model as the basis for inference is currently severely restricted by the computational challenge of estimating the likelihood. We discuss why the coalescent with recombination is so challenging to work with and...

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Identifiers

PMID: 16048782
DOI: 10.1098/rstb.2005.1673
PMCID: PMC1569517

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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