Article
The coalescent process in models with selection, recombination and geographic subdivision.
Genetical research - 1 Feb 1991
Kaplan N, Hudson R R, Iizuka M
Abstract excerpt
A population genetic model with a single locus at which balancing selection acts and many linked loci at which neutral mutations can occur is analysed using the coalescent approach. The model incorporates geographic subdivision with migration, as well as mutation, recombination, and genetic drift of neutral variation. It is found that geographic subdivision can affect genetic variation even with high rates of...
Topics
- Alcohol Dehydrogenase
- Animals
- Drosophila melanogaster
- Gene Frequency
- Mathematics
- Models, Genetic
- Mutation
- Recombination, Genetic
- Selection, Genetic