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Voltage-sensitive and ligand-gated channels in differentiating neural stem-like cells derived from the nonhematopoietic fraction of human umbilical cord blood.

Stem cells (Dayton, Ohio) - 1 Aug 2005

Sun Wei, Buzanska Leonora, Domanska-Janik Krystyna, Salvi Richard J, Stachowiak Michal K

Abstract excerpt

Fetal cells with the characteristics of neural stem cells (NSCs) can be derived from the nonhematopoietic fraction of human umbilical cord blood (HUCB), expanded as a nonimmortalized cell line (HUCB-NSC), and further differentiated into neuron-like cells (HUCB-NSCD); however, the functional and neuronal properties of these cells are poorly understood. To address this issue, we used whole-cell patch-clamp...

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PMID: 16043459
DOI: 10.1634/stemcells.2004-0316

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