Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Contemporaneous carrier-state of two or three "proatherosclerotic" variants of APOE, ICAM1, PPARA and PAI-1 genes differentiate CAD patients from healthy individuals.

Clinica chimica acta; international journal of clinical chemistry - 1 Dec 2005

Zak Iwona, Balcerzyk Anna, Sarecka Beata, Niemiec Paweł, Ciemniewski Zbigniew, Dylag Stanisław

Abstract excerpt

BACKGROUND: Atherosclerosis is the most important cause of coronary artery disease (CAD). Genetic predisposition to CAD is related to polymorphisms of genes encoding products functionally involved in pathogenesis of atherosclerosis. Polymorphisms of genes participating in monocyte adhesion and diapedesis, lipid metabolism and fibrinolysis regulation may be partially responsible for this process. The aim of our...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Apolipoproteins E
Share to Atherosclerosis

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Coronary Artery Disease

Share to Health

Share to Heterozygote

Share to Intercellular Adhesion Molecule-1

Share to Plasminogen Activator Inhibitor 1

Share to PPAR alpha

Source

Identifiers

PMID: 16043164
DOI: 10.1016/j.cccn.2005.06.011

Genes

CAD
ICAM1
PPARA
APOE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Contemporaneous carrier-state of two or three "proatherosclerotic" variants of APOE, ICAM1, PPARA and PAI-1 genes differentiate CAD patients from healthy individuals.PMID 16043164Read ↗

Carrier-state of two or three polymorphic variants of MTHFR, IL-6 and ICAM1 genes increases the risk of coronary artery disease.Semantic proximity Read ↗

Atherosclerotic and thrombotic genetic and environmental determinants in Egyptian coronary artery disease patients: a pilot study.Semantic proximity Read ↗

R643G polymorphism in PECAM-1 influences transendothelial migration of monocytes and is associated with progression of CHD and CHD eventsSemantic proximity Read ↗

Interactions between rs5498 polymorphism in the ICAM1 gene and traditional risk factors influence susceptibility to coronary artery disease.Semantic proximity Read ↗

Inflammatory and Prothrombotic Biomarkers, DNA Polymorphisms, MicroRNAs and Personalized Medicine for Patients with Peripheral Arterial DiseaseSemantic proximity Read ↗

Protective effect of R allele of PON1 gene on the coronary artery disease in the presence of specific genetic background.Semantic proximity Read ↗

The roles of PAI-1 gene polymorphisms in atherosclerotic diseases: A systematic review and meta-analysis involving 149,908 subjects.Semantic proximity Read ↗

A field synopsis and meta-analysis of genetic association studies in peripheral arterial disease: The CUMAGAS-PAD database.Semantic proximity Read ↗

Pro-inflammatory genetic profile and familiarity of acute myocardial infarctionSemantic proximity Read ↗

Polymorphism and synergism of angiotensin-converting enzyme (ACE) and plasminogen activator inhibitor-1 (PAI-1) genes in coronary artery disease.Semantic proximity Read ↗

ICAM-1 molecular mechanism and genome wide SNP's association studies.Semantic proximity Read ↗

Association of paraoxonase1 gene Q192R polymorphism and apolipoprotein B in Asian Indian women with coronary artery disease risk.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.