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A Novel Type of Immunity Protein, NukH, for the Lantibiotic Nukacin ISK-1 Produced by<i>Staphylococcus warneri</i>ISK-1

1 Jan 2005

Abstract excerpt

Staphylococcus warneri ISK-1 produces a lantibiotic, nukacin ISK-1. The nukacin ISK-1 gene cluster consists of at least six genes, nukA, -M, -T, -F, -E, and -G, and two open reading frames, ORF1 and ORF7 (designated nukH). Sequence comparisons suggested that NukF, -E, -G, and -H contribute to immunity to nukacin ISK-1. We investigated the immunity levels of recombinant Lactococcus lactis expressing nukFEG and...

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PMID: 16041148
DOI: 10.1271/bbb.69.1403

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