Article
Comparison ofHelicobacter pyloriVirulence Gene Expression In Vitro and in the Rhesus Macaque
23 Jul 2005
Abstract excerpt
We used a quantitative real-time reverse transcriptase PCR assay to measure the transcript abundance of 46 known and putative Helicobacter pylori virulence genes, including 24 genes on the Cag pathogenicity island. The expression profile of H. pylori cells grown in vitro was also compared to expression in vivo after experimental infection of rhesus macaques. Transcript abundance in vitro (mid-log phase) ranged...
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