Article
Performance of two commercially available sequence-based HIV-1 genotyping systems for the detection of drug resistance against HIV type 1 group M subtypes.
Journal of medical virology - 1 Jul 2003
Beddows Simon, Galpin Sarah, Kazmi Shamim H, Ashraf Ambreen, Johargy Ayman, Frater Alexander J, White Natalie, Braganza Ruth, Clarke John, McClure Myra, Weber Jonathan N
Abstract excerpt
The use of genotyping assays for the detection and evaluation of drug resistance mutations within the polymerase gene of human immunodeficiency virus type 1 (HIV-1) is becoming increasingly relevant in the clinical management of HIV-1 infection. However, genotypic resistance assays available currently have been optimised for genetic subtype B strains of the virus and many clinical centres are presented with...
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