Article
Measurement of HIV RNA in patients infected by subtype C by assays optimized for subtype B results in an underestimation of the viral load.
Journal of medical virology - 1 Jun 2004
Gottesman Bat-Sheva, Grosman Zehava, Lorber Margalit, Levi Itzchak, Shitrit Pnina, Mileguir Fernando, Gottesman Giora, Chowers Michal Y
Abstract excerpt
Quantitation assays of HIV-1 RNA used currently were designed and optimized for subtype B viruses. However, infection with non-B HIV viruses has become more common worldwide. Unfortunately, little information is available regarding the suitability of these assays for measurement of viral load in specific non-B subtypes. The performance of two commercial HIV-1 RNA quantitation assays was evaluated in 82 HIV...
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