Article
Mutation of the priA gene of Neisseria gonorrhoeae affects DNA transformation and DNA repair.
Journal of bacteriology - 1 Aug 2005
Kline Kimberly A, Seifert H Steven
Abstract excerpt
In Escherichia coli, PriA is central to the restart of chromosomal replication when replication fork progression is disrupted and is also involved in homologous recombination and DNA repair. To investigate the role of PriA in recombination and repair in Neisseria gonorrhoeae, we identified, cloned, and insertionally inactivated the gonococcal priA homologue. The priA mutant showed a growth deficiency and...
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