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Article

A Role for Human SPα as a Pattern Recognition Receptor

19 Jul 2005

Abstract excerpt

Human Sp alpha is a soluble protein belonging to group B of the scavenger receptor cysteine-rich (SRCR) superfamily for which little functional information is available. It is expressed by macrophages present in lymphoid tissues (spleen, lymph node, thymus, and bone marrow), and it binds to myelomonocytic and lymphoid cells, which suggests that it may play an important role in the regulation of the innate and...

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PMID: 16030018
DOI: 10.1074/jbc.m505042200

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