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The Evolution of the Scavenger Receptor Cysteine-Rich Domain of the Class A Scavenger Receptors

6 Jul 2015

Abstract excerpt

The class A scavenger receptor (cA-SR) family is a group of five evolutionarily related innate immune receptors. The cA-SRs are known for their promiscuous ligand binding; as they have been shown to bind bacteria, such as Streptococcus pneumoniae and Escherichia coli, as well as different modified forms of low-density lipoprotein. Three of the five family members possess a scavenger receptor cysteine-rich (SRCR)...

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PMID: 26217337
DOI: 10.3389/fimmu.2015.00342

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