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Article

Functional and structural conservation of CBS domains from CLC chloride channels.

The Journal of physiology - 1 Jun 2004

Estévez Raúl, Pusch Michael, Ferrer-Costa Carles, Orozco Modesto, Jentsch Thomas J

Abstract excerpt

All eukaryotic CLC Cl(-) channel subunits possess a long cytoplasmic carboxy-terminus that contains two so-called CBS (cystathionine beta-synthase) domains. These domains are found in various unrelated proteins from all phylae. The crystal structure of the CBS domains of inosine monophosphate deh...

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Source

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Identifiers

PMID: 14724190
DOI: 10.1113/jphysiol.2003.058453
PMCID: PMC1665104

Genes

CBS
CLC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-14724190-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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