Article
Mutational analysis of the promoter required for influenza virus virion RNA synthesis.
Journal of virology - 1 Jul 1992
Li X, Palese P
Abstract excerpt
An in vitro RNA synthesis system was established in which the influenza virus virion (minus-sense) RNA was made from the synthetic plus-sense RNA (cRNA) template by the purified viral polymerase complex. The cRNA promoter was studied by mutational analysis using the in vitro system, and on the ba...
Topics
- Base Sequence
- Chloramphenicol O-Acetyltransferase
- Cloning, Molecular
- DNA, Viral
- DNA-Directed RNA Polymerases
- Influenza A virus
- Introns
- Kinetics
- Molecular Sequence Data
- Mutation
- Plasmids
- Promoter Regions, Genetic
- RNA, Viral