Article
Mutational analysis of the promoter required for influenza virus virion RNA synthesis.
Journal of virology - 1 Jul 1992
Li X, Palese P
Abstract excerpt
An in vitro RNA synthesis system was established in which the influenza virus virion (minus-sense) RNA was made from the synthetic plus-sense RNA (cRNA) template by the purified viral polymerase complex. The cRNA promoter was studied by mutational analysis using the in vitro system, and on the basis of these experiments, the first 11 nucleotides of the 3' noncoding sequence were found to contain the minimum...
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