Article
A new method for reconstituting influenza polymerase and RNA in vitro: a study of the promoter elements for cRNA and vRNA synthesis in vitro and viral rescue in vivo.
Virology - 1 Jan 1992
Seong B L, Brownlee G G
Abstract excerpt
The influenza RNA polymerase is known to catalyse three distinct copying activities: (i) transcription of minus-sense virion RNA (vRNA) into mRNA, (ii) transcription of vRNA into full-length complementary RNA (cRNA), and (iii) transcription of cRNA to vRNA. Ever since the discovery of the conserv...
Topics
- Base Sequence
- DNA-Directed RNA Polymerases
- In Vitro Techniques
- Influenza A virus
- Macromolecular Substances
- Molecular Sequence Data
- Mutation
- Promoter Regions, Genetic
- RNA, Viral
- Ribonucleoproteins
- Templates, Genetic
- Transcription, Genetic