Article
Killer Ig-like receptor (KIR) compatibility plays a role in the prevalence of acute GVHD in unrelated hematopoietic cell transplants for AML.
Bone marrow transplantation - 1 Sept 2005
Sun J Y, Gaidulis L, Dagis A, Palmer J, Rodriguez R, Miller M M, Forman S J, Senitzer D
Abstract excerpt
Killer Ig-like receptor (KIR) is a major cluster of the natural killer cell receptors and may play a role in the outcome of hematopoietic cell transplants. A total of 65 AML cases transplanted with T-replete hematopoietic cells from unrelated donors were retrospectively KIR-genotyped by a multiplex PCR method of our own design. The KIR gene frequency and genotype patterns in these 130 samples were consistent with...
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