Article
Discrepancies between recombination frequencies and physical distances in Aspergillus nidulans: implications for gene identification.
Genetics - 1 Oct 2005
Espeso Eduardo A, Cobeño Laura, Arst Herbert N
Abstract excerpt
A rapid route to gene molecular identification involves using recombination frequencies in locating mutational sequence changes. We describe a case where the recombination frequency is deceptively low, probably reflecting centromere proximity. Recombination frequencies are greatly reduced near the centromeres on the right arms of chromosomes III and IV of Aspergillus nidulans.
Topics
- Aspergillus nidulans
- Base Sequence
- Centromere
- Chromosomes, Fungal
- Genes, Fungal
- Molecular Sequence Data
- Mutation
- Physical Chromosome Mapping
- Recombination, Genetic
- Sequence Analysis, DNA