Article
Evidence that low-level viremias during effective highly active antiretroviral therapy result from two processes: expression of archival virus and replication of virus.
Journal of virology - 1 Aug 2005
Tobin Nicole H, Learn Gerald H, Holte Sarah E, Wang Yang, Melvin Ann J, McKernan Jennifer L, Pawluk Diane M, Mohan Kathleen M, Lewis Paul F, Mullins James I, Frenkel Lisa M
Abstract excerpt
Episodes of low-level viremia (LLV), with plasma human immunodeficiency virus type 1 (HIV-1) RNA levels ranging from 50 to 400 copies (c)/ml, occur commonly during highly active antiretroviral therapy (HAART). LLV has been associated with virologic failure of HAART in some studies, while in others LLV did not appear to affect the clinical outcome. To understand the processes leading to LLV, genetic analyses were...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.