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Article

An essential role of the enhancer for murine cytomegalovirus in vivo growth and pathogenesis.

Journal of virology - 1 Mar 2003

Ghazal Peter, Messerle Martin, Osborn Kent, Angulo Ana

Abstract excerpt

The transcription of cytomegalovirus (CMV) immediate-early (IE) genes is regulated by a large and complex enhancer containing an array of binding sites for a variety of cellular transcription factors. Previously, using bacterial artificial chromosome recombinants of the virus genome, it was reported that the enhancer region of murine CMV (MCMV) is dispensable but performs a key function for viral multiplication...

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Share to Chromosomes, Artificial, Bacterial
Share to Enhancer Elements, Genetic

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Gene Expression Regulation, Viral

Share to Herpesviridae Infections

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Share to Mice, SCID

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Source

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Identifiers

PMID: 12584345
DOI: 10.1128/jvi.77.5.3217-3228.2003
PMCID: PMC149741

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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