Article
Cine MR imaging of myocardial contractile impairment in patients with hypertrophic cardiomyopathy attributable to Asp175Asn mutation in the alpha-tropomyosin gene.
Radiology - 1 Sept 2005
Sipola Petri, Lauerma Kirsi, Jääskeläinen Pertti, Laakso Markku, Peuhkurinen Keijo, Manninen Hannu, Aronen Hannu J, Kuusisto Johanna
Abstract excerpt
PURPOSE: To prospectively investigate the relationship between myocardial contractile impairment and left ventricular (LV) hypertrophy measured at cardiac magnetic resonance (MR) imaging in patients with hypertrophic cardiomyopathy (HCM) caused by the substitution of aspartic acid 175 with asparagine (ie, Asp175Asn mutation) in the alpha-tropomyosin gene (TPM1). MATERIALS AND METHODS: The study protocol was...
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