First-pass MR imaging in the assessment of perfusion impairment in patients with hypertrophic cardiomyopathy and the Asp175Asn mutation of the alpha-tropomyosin gene.

doi:10.1148/radiol.2261011874

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First-pass MR imaging in the assessment of perfusion impairment in patients with hypertrophic cardiomyopathy and the Asp175Asn mutation of the alpha-tropomyosin gene.

Radiology - 1 Jan 2003

Sipola Petri, Lauerma Kirsi, Husso-Saastamoinen Minna, Kuikka Jyrki T, Vanninen Esko, Laitinen Tomi, Manninen Hannu, Niemi Pekka, Peuhkurinen Keijo, Jääskeläinen Pertti, Laakso Markku, Kuusisto Johanna, Aronen Hannu J

Abstract excerpt

PURPOSE: To assess first-pass magnetic resonance (MR) imaging in the evaluation of perfusion impairment in a genetically homogeneous population of patients with hypertrophic cardiomyopathy (HCM) and the Asp175Asn mutation of the alpha-tropomyosin gene and to evaluate the association between hypertrophy and perfusion. MATERIALS AND METHODS: Rest-stress first-pass MR imaging with gadopentetate dimeglumine was...

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First-pass MR imaging in the assessment of perfusion impairment in patients with hypertrophic cardiomyopathy and the Asp175Asn mutation of the alpha-tropomyosin gene.

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