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Article

A prospective evaluation of the transthyretin Ile122 allele frequency in an African-American population.

Amyloid : the international journal of experimental and clinical investigation : the official journal of the International Society of Amyloidosis - 1 Jun 2005

Yamashita Taro, Hamidi Asl Kamran, Yazaki Masahide, Benson Merrill D

Abstract excerpt

Transthyretin Val122Ile is one of greater than 80 mutations in transthyretin (TTR) that are associated with hereditary amyloidosis. Retrospective studies have shown a prevalence of this mutation as high as 3.9% in African-Americans. The present study was undertaken to determine in a prospective fashion the prevalence of the TTR Val122Ile allele in African-Americans in a Midwestern American city. DNA was isolated...

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Identifiers

PMID: 16011990
DOI: 10.1080/13506120500107162

Genes

TTR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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A prospective evaluation of the transthyretin Ile122 allele frequency in an African-American population.PMID 16011990Read ↗

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The prevalence and distribution of the amyloidogenic transthyretin ( <i> <scp>TTR</scp> </i> ) V122I allele in AfricaSemantic proximity Read ↗

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Significance of the amyloidogenic transthyretin Val 122 Ile allele in African Americans in the Arteriosclerosis Risk in Communities (ARIC) and Cardiovascular Health (CHS) Studies.Semantic proximity Read ↗

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Frequency and genetic background of the position 122 (Val----Ile) variant transthyretin gene in the black population.Semantic proximity Read ↗

Transthyretin Ile 122 and cardiac amyloidosis in African-Americans. 2 case reports.Semantic proximity Read ↗

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