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Article

Revised transthyretin Ile 122 allele frequency in African-Americans.

Human genetics - 1 Aug 1996

Jacobson D R, Pastore R, Pool S, Malendowicz S, Kane I, Shivji A, Embury S H, Ballas S K, Buxbaum J N

Abstract excerpt

The transthyretin (TTR) Ile 122 variant is associated with cardiac amyloidosis in individuals of African descent. To determine the prevalence of the allele encoding TTR Ile 122 in African-Americans, we have used PCR and restriction analysis to test DNA from African-Americans from various geographic areas, and found an allele frequency of 66/3376 (0.020), which is higher than the value we previously reported in a...

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Source

Identifiers

PMID: 8698351
DOI: 10.1007/s004390050199

Genes

TTR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

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Revised transthyretin Ile 122 allele frequency in African-Americans.PMID 8698351Read ↗

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