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Article

Transthyretin Ile 122 and cardiac amyloidosis in African-Americans. 2 case reports.

Texas Heart Institute journal - 1 Jan 1997

Jacobson D R, Ittmann M, Buxbaum J N, Wieczorek R, Gorevic P D

Abstract excerpt

Two cases of cardiac amyloidosis resulting from deposition of the Ile 122 variant of transthyretin in African-Americans are presented. These cases illustrate several typical features of this disorder, including electrocardiographic abnormalities and digoxin toxicity. Transthyretin Ile 122 is a common amyloidogenic variant in African-Americans (present as a heterozygous variant in 4% of this population);...

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Identifiers

PMID: 9068139
PMCID: PMC325397

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Transthyretin Ile 122 and cardiac amyloidosis in African-Americans. 2 case reports.PMID 9068139Read ↗

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