Article
Anthrax toxin receptor 2 mediates Bacillus anthracis killing of macrophages following spore challenge.
Cellular microbiology - 1 Aug 2005
Banks David J, Barnajian Moshe, Maldonado-Arocho Francisco J, Sanchez Ana M, Bradley Kenneth A
Abstract excerpt
Initiation of inhalation anthrax is believed to involve phagocytosis of Bacillus anthracis spores by alveolar macrophages, followed by spore germination within the phagolysosome. In order to establish a systemic infection, it is predicted that bacilli then escape from the macrophage and replicate extracellularly. Mechanisms utilized by B. anthracis to escape from the macrophage are not well characterized, but a...
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