Article
Association of the OSCAR promoter polymorphism with BMD in postmenopausal women.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research - 1 Aug 2005
Kim Ghi Su, Koh Jung-Min, Chang Jae Suk, Park Byung Lae, Kim Lyoung Hyo, Park Eui Kyun, Kim Shin-Yoon, Shin Hyoung Doo
Abstract excerpt
UNLABELLED: In an effort to identify genetic polymorphisms in potential candidate genes for osteoporosis, 10 variants were identified in the OSCAR gene using direct DNA sequencing, and 560 postmenopausal women were genotyped at five SNP loci, using the TaqMan method. The rare allele (G allele) of OSCAR-2322A>G (SNP in the 5' flanking region) showed significant association with lower BMD at various bone sites in...
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