Article
Heparin-binding epidermal growth factor-like growth factor, collateral vessel development, and angiogenesis in skeletal muscle ischemia.
Arteriosclerosis, thrombosis, and vascular biology - 1 Sept 2005
Chalothorn Dan, Moore Scott M, Zhang Hua, Sunnarborg Susan W, Lee David C, Faber James E
Abstract excerpt
OBJECTIVE: Heparin-binding epidermal growth factor-like growth factor (HB-EGF) is a potent mitogen for smooth muscle cells and has been implicated in atherosclerosis, tissue regeneration after ischemia, vascular development, and tumor angiogenesis. We examined the hypothesis that HB-EGF participates in angiogenesis and collateral growth in ischemia. METHODS AND RESULTS: During 3 weeks after femoral artery...
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