Article
Serum glucose concentration and ACP1 genotype in healthy adult subjects.
Metabolism: clinical and experimental - 1 Jul 2005
Iannaccone Umberto, Bergamaschi Antonio, Magrini A, Marino Giuseppe, Bottini Nunzio, Lucarelli Paola, Bottini Egidio, Gloria-Bottini Fulvia
Abstract excerpt
Acid phosphatase locus 1 (ACP 1 ) or cytosolic low molecular weight protein tyrosine phosphatase is a polymorphic enzyme that can hydrolyze phosphotyrosine-containing peptides of the human insulin receptor and of band 3 protein. High-activity ACP 1 may favor an increase in serum glucose concentration through a depression of insulin action and through inactivation of aldolase, phosphofructokinase, and...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
