Article
Effect of pregnancy as a risk factor for breast cancer in BRCA1/BRCA2 mutation carriers.
International journal of cancer - 20 Dec 2005
Cullinane Carey A, Lubinski Jan, Neuhausen Susan L, Ghadirian Parviz, Lynch Henry T, Isaacs Claudine, Weber Barbara, Moller Pal, Offit Kenneth, Kim-Sing Charmaine, Friedman Eitan, Randall Susan, Pasini Barbara, Ainsworth Peter, Gershoni-Baruch Ruth, Foulkes William D, Klijn Jan, Tung Nadine, Rennert Gad, Olopade Olufunmilayo, Couch Fergus, Wagner Teresa, Olsson Hakan, Sun Ping, Weitzel Jeffrey N, Narod Steven A
Abstract excerpt
Early age at first birth and multiparity have been associated with a decrease in the risk of breast cancer in women in the general population. We examined whether this relationship is also present in women at high risk of breast cancer due to the presence of a mutation in either of the 2 breast cancer susceptibility genes, BRCA1 or BRCA2. We performed a matched case-control study of 1,260 pairs of women with...
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