Article
Gender specificity of programmed plasma hypertonicity and hemoconcentration in adult offspring of water-restricted rat dams.
Journal of the Society for Gynecologic Investigation - 1 Sept 2005
Desai Mina, Gayle Dave, Kallichanda Nathash, Ross Michael G
Abstract excerpt
OBJECTIVE: We studied the impact of maternal water-restriction during rat pregnancy on newborn plasma composition, and determined the persistence of plasma composition alterations in adult offspring. METHODS: Maternal dams were water-restricted from 10 days of pregnancy until term (21 days) and throughout lactation to increase plasma sodium levels by approximately 6 mEq/L. At 21 days of age, offspring were...
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