Article
Elucidation of thrifty features in adult rats exposed to protein restriction during gestation and lactation.
Physiology & behavior - 20 Mar 2012
Qasem Rani J, Yablonski Elizabeth, Li Jing, Tang Hee Man, Pontiggia Laura, D'mello Anil P
Abstract excerpt
Since the introduction of the thrifty phenotype hypothesis, the potential traits of thrift have been described in increasingly broad terms but biochemical and behavioral evidence of thrift has not been well demonstrated. The objective of our studies was to use a rodent model to identify features of thrift programmed by early life protein restriction. Robust programming of thrifty features requires a thrifty...
Topics
- Adaptation, Physiological
- Animals
- Birth Weight
- Body Composition
- Body Temperature
- Body Weight
- Diet, Protein-Restricted
- Energy Metabolism
- Female
- Ghrelin
- Insulin Resistance
