Article
Protein kinase A-dependent phosphorylation of Lutheran/basal cell adhesion molecule glycoprotein regulates cell adhesion to laminin alpha5.
The Journal of biological chemistry - 26 Aug 2005
Gauthier Emilie, Rahuel Cécile, Wautier Marie Paule, El Nemer Wassim, Gane Pierre, Wautier Jean Luc, Cartron Jean Pierre, Colin Yves, Le Van Kim Caroline
Abstract excerpt
Lutheran (Lu) blood group and basal cell adhesion molecule (B-CAM) antigens reside on two glycoprotein (gp) isoforms Lu and Lu(v13) that belong to the Ig superfamily and differ only by the size of their cytoplasmic tail. Lu/B-CAM gps have been recognized as laminin alpha5 receptors on red blood cells and epithelial cells in multiple tissues. It has been shown that sickle red cells exhibit enhanced adhesion to...
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