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AAV Hybrid Serotypes: Improved Vectors for Gene Delivery

1 Jun 2005

Abstract excerpt

In recent years, significant efforts have been made on studying and engineering adeno-associated virus (AAV) capsid, in order to increase efficiency in targeting specific cell types that are non-permissive to wild type (wt) viruses and to improve efficacy in infecting only the cell type of interest. With our previous knowledge of the viral properties of the naturally occurring serotypes and the elucidation of...

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PMID: 15975007
DOI: 10.2174/1566523054064968

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