Article
Sequence diversity and antigenic variation at the rag locus of Porphyromonas gingivalis.
Infection and immunity - 1 Jul 2005
Hall Lucinda M C, Fawell Stuart C, Shi Xiaoju, Faray-Kele Marie-Claire, Aduse-Opoku Joseph, Whiley Robert A, Curtis Michael A
Abstract excerpt
The rag locus of Porphyromonas gingivalis W50 encodes RagA, a predicted tonB-dependent receptor protein, and RagB, a lipoprotein that constitutes an immunodominant outer membrane antigen. The low G+C content of the locus, an association with mobility elements, and an apparent restricted distribution in the species suggested that the locus had arisen by horizontal gene transfer. In the present study, we have...
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